The Central Brain Tumor Registry of the United States (CBTRUS) maintains and regularly updates a database of primary malignant and non-malignant tumors of the brain, other central nervous system (CNS), tumors of the pituitary and pineal glands, olfactory tumors of the nasal cavity, and brain lymphoma and leukemia. These data are the source of the 2025 CBTRUS Statistical Report, the 2026 CBTRUS Fact Brochure, CBTRUS peer-reviewed publications, and the statistical facts and information shown on this page.

CBTRUS presents incidence data on all newly diagnosed primary brain and other CNS tumors from two national sources: the Centers for Disease Control and Prevention’s (CDC) National Program of Cancer Registries (NPCR) and the National Institute of Health’s National Cancer Institute’s (NCI) Surveillance, Epidemiology and End Results (SEER) Program. Cancer surveillance data (of all types of cancer) from these two programs are combined and are referred to as the United States Cancer Statistics (USCS), the official source for federal cancer data. There are 52 population-based central cancer registries that contribute to this data collection effort. They include cancer registries from all 50 states plus the District of Columbia and Puerto Rico. These data represent nearly 100% of the United States population.