CBTRUS Statistical Report:

Primary Brain and Central Nervous System Tumors Diagnosed in the United States in 2014-2018

This report was prepared by the CBTRUS Scientific Co-Scientific Principal Investigators Jill Barnholtz-Sloan, Ph.D. and CBTRUS Team members at the Department of Cancer Epidemiology and Genetics at the National Cancer Institute and,and Quinn Ostrom, Ph.D. M.P.H. and CBTRUS Team members from Duke University, Department of Neurosurgery, Duke University School of Medicine; and CBTRUS President and Chief Mission Officer Carol Kruchko. The CBTRUS data presented in this report were provided through an agreement with the Centers for Disease Control and Prevention (CDC), National Program of Cancer Registries (NPCR). In addition, CBTRUS used data from the research data sets of the National Cancer Institute, Surveillance, Epidemiology, and End Results (SEER) Program. CBTRUS acknowledges and appreciates these contributions to this report and to cancer surveillance in general and in particular to the efforts of the hospital tumor registrars, the central cancer registries, and the staff from the NPCR and SEER programs whose efforts to collect accurate and complete data have made this report possible.

We are also grateful to the four neuropathologists, Drs. Janet Bruner, Roger McLendon, Tarik Tihan, and Daniel Brat, who advised us on the realignment of the CBTRUS histology grouping scheme to 2016 WHO Classification, to our Consulting Neuropathologist, Dr. Janet Bruner who answered our questions and provided feedback throughout the year, to our Board of Directors and Advisors who reviewed this report, and especially Drs. Hoda Anton-Culver, Melissa Bondy, Faith Davis, and to Claudia Smits, LLM and Reda J. Wilson, M.P.H., CTR.

Sources of geographic population-based cancer incidence data for 2014-2018 included in this report are from the following 52 central cancer registries (CCR):

Alabama Montana
Alaska Nebraska
Arizona Nevada*
Arkansas New Hampshire
California New Jersey
Colorado New Mexico (SEER)
Connecticut (SEER) New York
Delaware North Carolina
District of Columbia North Dakota
Florida Ohio
Georgia Oklahoma
Hawaii (SEER) Oregon
Idaho Pennsylvania
Illinois Rhode Island
Indiana South Carolina
Iowa (SEER) South Dakota
Kansas Tennessee
Kentucky Texas
Louisiana Utah
Maine Vermont
Maryland Virginia
Massachusetts Washington
Michigan West Virginia
Minnesota Wisconsin
Mississippi Wyoming

(SEER) Data were obtained from the SEER research data files, 2013-2016 for these population-based cancer registries for incidence calculations. All other population-based cancer registry data provided by the NPCR, which may include registries for which data are also available through SEER.

*Data for 2014-2017 only

Sources of geographic population-based cancer survival data for 2001-2017 included in the 2021 CBTRUS Report are from 45 central cancer registries (CCR) of the NPCR Program:

Alabama Nebraska
Arizona New Hampshire
Arkansas New Jersey
California New York
Colorado North Carolina
Delaware North Dakota
District of Columbia Ohio
Florida Oklahoma
Georgia Oregon
Idaho Pennsylvania
Illinois Rhode Island
Kansas South Carolina
Kentucky Tennessee
Louisiana Texas
Maine Utah
Maryland Vermont
Minnesota West Virginia
Mississippi Wisconsin
Missouri Wyoming

Citation: Quinn T. Ostrom, Ph.D., M.P.H., , Gino Cioffi, M.P.H., Kristin Waite, Ph.D., Carol Kruchko, B.A., and Jill S. Barnholtz-Sloan, Ph.D., CBTRUS Statistical Report: Primary Brain and Other Central Nervous System Tumors Diagnosed in the United States in 2014-2018, 0) Neuro-Oncology, Volume , Issue Supplement 1, October 2021, Pages iv1-iv, https//