CBTRUS Statistical Report:

Primary Brain and Central Nervous System Tumors Diagnosed in the United States in 2015-2019

This report was prepared by the CBTRUS Scientific Co-Scientific Principal Investigators Quinn Ostrom, Ph.D., M.P.H. and her research team from Duke University, Department of Neuro-Surgery, Duke University School of Medicine in collaboration with Co-Scientific Principal Investigator Jill Barnholtz-Sloan, Ph.D., the research staff affiliated with the National Cancer Institute (NCI) Division of Epidemiology and Genetics, and CBTRUS President and Chief Mission Officer Carol Kruchko, collectively known as the CBTRUS Scientific Team.

The CBTRUS data presented in this report were provided through an agreement with the Centers for Disease Control and Prevention (CDC), National Program of Cancer Registries (NPCR). In addition, CBTRUS used data from the research data sets of the NCI, Surveillance, Epidemiology, and End Results (SEER) Program. CBTRUS acknowledges and appreciates these contributions to this report and to cancer surveillance in general and in particular to the efforts of the hospital tumor registrars, the central cancer registries, and the staff from the NPCR and SEER programs whose efforts to collect accurate and complete data have made this report possible.

We are also grateful to our Consulting Neuropathologist, Dr. Janet Bruner who answered our questions and provided feedback throughout the year, to our Board of Directors and Advisors,  and especially Melissa Bondy, Ph.D., Elizabeth Claus, M.D., Ph.D., Nancy Stroup, Ph.D., and to Claudia Smits, LLM, Reda J. Wilson, M.P.H., CTR, and Mary Elizabeth O’Neil, M.P.H., who reviewed this report.

Sources of geographic population-based cancer incidence data for 2015-2019 included in this report are from the following 52 central cancer registries (CCR):

Alabama Montana
Alaska Nebraska
Arizona Nevada*
Arkansas New Hampshire
California New Jersey
Colorado New Mexico (SEER)
Connecticut (SEER) New York
Delaware North Carolina
District of Columbia North Dakota
Florida Ohio
Georgia Oklahoma
Hawaii (SEER) Oregon
Idaho Pennsylvania
Illinois Rhode Island
Indiana South Carolina
Iowa (SEER) South Dakota
Kansas Tennessee
Kentucky Texas
Louisiana Utah
Maine Vermont
Maryland Virginia
Massachusetts Washington
Michigan West Virginia
Minnesota Wisconsin
Mississippi Wyoming

(SEER) Data were obtained from the SEER research data files for these population-based cancer registries for incidence calculations. All other population-based cancer registry data provided by the NPCR, which may include registries for which data are also available through SEER.

*Data not available for diagnosis years 2018-2019

Sources of geographic population-based cancer survival data for 2001-2018 included in the 2022 CBTRUS Report are from 42 central cancer registries (CCR) of the NPCR Program:

Alabama Nebraska
Alaska Nevada
Arizona New Hampshire
Arkansas New Jersey
California New York
Colorado North Carolina
Delaware North Dakota
Florida Oklahoma
Georgia Oregon
Idaho Pennsylvania
Illinois Rhode Island
Kansas South Dakota

South Carolina

Kentucky Tennessee
Louisiana Texas
Maine Utah
Maryland Vermont
Minnesota West Virginia
Mississippi Wisconsin
Missouri Wyoming

Citation: Quinn T. Ostrom, Ph.D., M.P.H., Mackenzie Price, M.P.H., Corey Neff, M.P.H., Gino Cioffi, M.P.H., Kristin Waite, Ph.D., Carol Kruchko, B.A., and Jill S. Barnholtz-Sloan, Ph.D., CBTRUS Statistical Report: Primary Brain and Other Central Nervous System Tumors Diagnosed in the United States in 2015-2019, Neuro-Oncology, Volume 24, Issue Supplement 5, October 2022, Pages v1-v95, https//